分子量:15.1 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human Cystatin SN, His Tag by the LAL method.

Buffer:25 mM MES, 150 mM NaCl, pH 6.0

生物活性:

产品特性:Human Cystatin SN, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 15.1 kDa. The predicted N-terminus is Trp 21. The reducing (R) protein migrates as 17-19 kDa in SDS-PAGE .

产品背景:Cystatin-1 (CST1) is also known as Cystatin-SN, Cystain-SA-I, Salivary cystatin-SA-1, which is secreted protein and belongs to the cystatin family. Cystatin-1 is expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level) and also expressed in saliva, tears, urine and seminal fluid. Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well.