FITC标记的TRIM68蛋白抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的TRIM68蛋白抗体

FITC标记的TRIM68蛋白抗体

商家询价

产品名称: FITC标记的TRIM68蛋白抗体

英文名称: Anti-TRIM68/FITC

产品编号: HZ-

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-TRIM68/FITC Conjugated antibody

FITC标记的TRIM68蛋白抗体

 

英文名称 Anti-TRIM68/FITC
中文名称 FITC标记的TRIM68蛋白抗体
别    名 E3 ubiquitin-protein ligase TRIM68; FLJ10369; GC109; MGC126176; RING finger protein 137; RNF 137; RNF137; Ro/SSA1 related protein; SS 56; SS-56; SS56; SSA protein SS 56; SSA protein SS-56; TRI68_HUMAN; TRIM 68; Trim68; Tripartite motif containing 68; Tripartite motif containing protein 68; Tripartite motif-containing protein 68.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  免疫学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TRIM68
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a protein which contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is expressed in many cancer cell lines. Its expression in normal tissues, however, was found to be restricted to prostate. This gene was also found to be differentially expressed in androgen-dependent versus androgen-independent prostate cancer cells. [provided by RefSeq, Oct 2011]

Function:
Functions as an ubiquitin E3 ligase. Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.

Subunit:
Interacts with AR/androgen receptor (via ligand-binding domain). Interacts with KAT5/TIP60. 

Subcellular Location:
Cytoplasm > perinuclear region. Nucleus. Colocalized with AR in nucleus.

Tissue Specificity:
Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.

Post-translational modifications:
Auto-ubiquitinated.

Similarity:
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 55128 Human

Entrez Gene: 101700 Mouse

Omim: 613184 Human

SwissProt: Q6AZZ1 Human

SwissProt: Q8K243 Mouse

Unigene: 523438 Human

Unigene: 738828 Human

Unigene: 39043 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

这个基因编码蛋白,包含了有环指域,图案present in a variety of functionally单独的蛋白质和known to be involved in蛋白-蛋白与DNA相互作用的蛋白。这是基因的表达在许多癌细胞线。其表达在正常组织,然而,was found to be restricted to前列腺。这个基因was also found to be差异表达雄与雄依赖性前列腺癌细胞无关。[ provided by RefSeq,2011年10月)